This Milk-Jug-Size Device Can Help Newborns Breathe

The milk-jug-size Third Pole generates nitric oxide (NO) from the air to improve oxygenation and treat pulmonary hypertension, a common ailment among newborns, without bulky tanks or regulators.


  • Warren and David Zapol
  • Ages: 75 and 45
  • Co-founders of Third Pole Inc., an eight-employee startup in San Francisco and Arlington, Mass.

1. Setup

A clinician determines the appropriate NO dosage to saturate the patient with oxygen, then inserts a nasal tube connected to the Third Pole and switches it on.

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