The researchers initially discovered that insulin-producing beta-cells include a big quantity of a cell surface receptor for vitamin A.
“There are not any unnecessary surface receptors in human cells. All of them serve a objective but which, in many instances, continues to be unknown and because of that they’re referred to as “orphan” receptors. Once we found that insulin cells have a cell floor expressed receptor for vitamin A, we thought it was necessary to seek out out why and what the purpose is of a cell floor receptor interacting with vitamin A mediating a speedy response to vitamin A”, explains Albert Salehi, senior researcher at the Lund College Diabetes Centre in Sweden.
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