Repurposing anti-hypertension drug for type 1 diabetes


Finger pricks and daily insulin injections are currently the leading regimen for those with type 1 diabetes, a condition in which the body’s insulin producing cells beta cells are destroyed. And it’s not foolproof.

Patients can often face risks over overcorrecting their blood sugar levels, which can potentially lead to hypoglycemia — low blood sugar — and coma.

Insulin is responsible for regulating the amount of sugar in the blood, and dysfunctions with it can cause diabetes. There are two types of diabetes, type 2 diabetes, in which the body becomes insulin resistant and can’t effectively use it, and type 1 diabetes, in which the immune system destroys large portions of the beta cells responsible for making insulin in the pancreas. In 2015, the Centers for Disease Control and Prevention reported that over 30 million people in the US had diagnosed diabetes, and about 5% of them had type 1 diabetes.

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