Pulmonary Arterial Hypertension Outcomes With Atrial Arrhythmia










The worst outcomes were seen in patients with systemic sclerosis-related pulmonary arterial hypertension and atrial arrhythmia.




Patients with idiopathic or systemic sclerosis-related pulmonary arterial hypertension (PAH) who developed atrial arrhythmias had increased right atrial pressure, pulmonary wedge pressure, and thyroid disease prevalence, according to a recent study published in Pulmonary Circulation.

Baseline measurements were taken of patients with either idiopathic (n=116) or systemic sclerosis-related (n=201) PAH. Health outcomes related to development of atrial arrhythmia were tracked prospectively and compared with those patients who did not develop atrial arrhythmia.

Of the 42 (13.2%) participants who developed atrial arrhythmia, 90.5% of cases resulted in hospitalization. Atrial arrhythmia was also associated with higher right atrial pressure, pulmonary wedge pressure (P <.005), NT-proBNP (P <.05), and thyroid disease prevalence (P <.005). 

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