OHSU scientist isolate, visualize key protein in regulating blood pressure

by Stuart Tomlinson, KATU News

Using a powerful electron microscope, researchers at OHSU’s Vollum Institute have been able to see inside a protein that regulates the salt and water balance in our bodies. (OHSU)

Using a powerful electron microscope, researchers at OHSU’s Vollum Institute have been able to see inside a protein that regulates the salt and water balance in our bodies.

It’s a first step in being able to target the protein with drugs to regulate high blood pressure — the silent killer.

“What we’re seeing here are three different proteins that come together and form this ion channel that can let sodium go through,” said graduate student Sigrid Noreng and lead author of the study on the protein. “In certain cases, it will be a closed channel, where it won’t let sodium go through.”

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